Elsiabeth Jones

Had pelvic radiation as part of my initial Stage 3 treatment (TNT approach). James’ advice is spot on. Hydration is key. For bladder irritation, avoiding caffeine and acidic drinks helped me. The fatigue builds up, so plan for rest. Sitz baths (warm, shallow baths) can be soothing for skin irritation too, but check with your team first.

Also MSI-stable, so no firsthand immunotherapy experience, but sending positive thoughts for continued success with Keytruda for your husband, Karen! Fatigue is just part of the cancer battle, regardless of treatment type, it seems.

Still have my port, it’s my lifeline for FOLFIRI/Avastin infusions. Placement was okay, some bruising. Access is routine now, numbing cream helps. I did have one suspected infection scare (redness, warmth) - turned out okay after antibiotics, but scary! They monitor it closely. Always report any redness, swelling, pain near the site immediately.

FOLFOX is doable. Fatigue was significant for me, cumulative. Listen to your body, rest when needed. And yes to scheduled anti-nausea meds. I also found Lorazepam (Ativan) helpful for anticipatory nausea before infusions.

Thanks Elizabeth. Hearing you had a similar starting plan helps normalize it a tiny bit. “Be kind to yourself” - easier said than done right now, but I appreciate it.

John, I’m so sorry you’re starting this journey. I had Stage 3 rectal initially too (chemo/rads first, then surgery). That diagnosis day is seared into memory. Allow yourself to feel whatever you feel. Numb is normal. Scared is normal. There’s no right way to react. Be kind to yourself.